U.S. famous talk-show host Larry King has filed for divorce from his wife Shawn Southwick-King in Los Angeles on Wednesday, according to reports of AP.

Larry King, 76, is best known for his interview show "Larry King Live" and owns a wide and stable audience.

R&B singer Chris Brown (R) is interviewed by CNN talk show host Larry King (L) with Brown's mother Joyce Hawkins at CNN studios in Los Angeles August 26, 2009 in this publicity photograph from CNN. [Xinhua/Reuters]

He filed to end the 13-year marriage with his seventh wife, citing “irreconcilable differences."

They got married in 1997 just after he received a surgery to clear a clogged blood vessel.

The couple have two sons, ages 11 and 9. King is seeking joint custody of the boys.

"His major concern is the welfare of his children," said Howard Rubenstein, a spokesman for King, adding the talk-show host would not comment further on the divorce.

King has three children from previous relationships.